DebutFawad had been interested in the media business ever since childhood and his introduction into the world of show business was, as he puts it, "quite planned."  Khan's first public performance was in a high school play directed by a friend of his, Zain Ahmed. The play caught the attention of director Shahzad Anjum, who helped Fawad into the media world. Khan first found fame when he was 22-years old by playing bumbling spy role in Jutt and Bond which also starred his friend and co-band member, Ahmed Ali Butt. He and Butt started their band, Entity Paradigm, around this time.
Television serials and Khuda Kay Liye (2007-present)Fawad starred in a number of drama serials until he was finally opted as the role Sarmad in the movie Khuda Kay Liye. The film was a great milestone not only for the Pakistani entertainment business, but for Khan as well. When questioned if Khan would favor stepping into Bollywood, he said "I will only go for it if it [Bollywood movie] is based on a quality project. Otherwise, Pakistan is my first priority, and I love working for my country."
In year 2008, Khan appeared in Anjum Shehzad's travel and adventure drama series Satrangi. Khan portrayed the role of an engineering student who hires a mini-bus and takes his six friend to a trip around the country. Khan had also wrote and sang the original soundtrack of the drama.
Fawad has been seen in various commercial advertisements for companies like Olper's, Pepsi and Mobilink Jazz. He has also walked the ramp for designer Muneeb Nawaz and in the following year Khan modeled for clothing brand Levi's Pakistan and fashion designer Ammar Belal.
In year 2010 Fawad's band, Entity Paradigm, which broke up around 2007, got reunited and performed Bolo Bolo in Season 3 of popular television music series Coke Studio. Later in the year EP also released their breakthrough album Shor Macha. In which the title track with strong patriotic message became relatively more popular. Khan, at the launch of the album, commented on the track, "The message is for people to stop complaining and start acting.
In the same year Fawad landed a lead role of Hassan beside actress Sanam Baloch who portrayed the role of Bano, in director Haissam Hussain's mega project Dastaan on Hum TV. Khan stated in telephonic interview with breakfast show, Morning with Hum, that Dastaan was a project that "could not be refused." The serial received a lot of praise from audiences and went on to receive many awards and nominations.
Fawad's newest drama serial is an adaptation of writer Farhat Ishtiaq's novel, Humsafar. The cast includes Mahira Khan, Atiqa Odho and VJ turned actress Naveen Waqar. Khan was also set to play lead in another of Farhat Ishtiaq's dramas directed by award-winning director Mehreen Jabbar, Mata-e-Jaan but backed out due to scheduling conflicts. Currently he is working on his next two projects Zindagi Gulzar Hai and Bandhan. Both the serials are produced by MD Productions for Hum TV and will be airing in the first quarter of 2012. He also has a role in Annie Ki Aayegi Baraat as a son of Javed Sheikh, which will air on 7th of April 2012.